Salute e Benessere
HKBU leads the development of multifunctional nanorobots for precise and effective pollutant degradation and bacterial removal
Professor Ken Leung Cham -fai, Associate Professor of the Department of Chemistry at HKBU, in collaboration with scientists from the University of Science and Technology of China , Hefei University of Technology, and the Dongcheng branch of the First Affiliated Hospital of Anhui Medical University, have designed and fabricated a nanorobot, which demonstrates capabilities in breaking down organic pollutants, exhibits antibacterial properties, and removes biofilms. The research findings have been published in the academic journal
The multifunctional nanorobot has a hollow spherical structure with the following components and features:
To test the efficacy of the nanorobot in pollutant degradation, the research team created simulated miniature wastewater pools. Driven by magnetic fields, the nanorobots accurately moved to two of the chambers and stayed there for one minute. Subsequent tests showed that the levels of both 4-nitrophenol, an organic pollutant from industrial and agricultural activities, and methylene blue, an organic dye typically found in industrial wastewater, were reduced significantly.
The research team also discovered that the nanorobot demonstrates antibacterial capability. The team used the nanorobot loaded with zinc phthalocyanine to investigate the antibacterial effects of silver and gold on
and under various conditions, including controlling the nanorobots' movement with magnetic fields, and applying light sources including near-infrared laser and xenon lamp irradiation. When magnetic fields, near-infrared laser and xenon lamp irradiation were applied together, the nanorobot loaded with zinc phthalocyanine achieved up to 99.99% inhibition of bacterial proliferation.
The magnetic propulsion capability of the nanorobot loaded with zinc phthalocyanine also enables it to effectively remove bacterial biofilms. When the nanorobots were introduced to biofilms grown in experiment plates, and U-shaped tubes with magnetic fields and light source were applied, they effectively disrupted and removed biofilms. When magnetic fields, near-infrared laser and xenon lamp irradiation were applied together, the most significant biofilm removal and lowest bacterial survival rates were recorded. The study highlights the potential of the nanorobot in addressing biofilm-associated infections and blockages in confined spaces like catheters.
Professor Ken Leung Cham -fai said: "Our research results show that the multifunctional nanorobot developed by our research team exhibits precise catalytic capabilities, high antibacterial activity, and effective biofilm removal properties. Its mobility navigated by magnetic fields enables pollutant degradation and antibacterial activities to be conducted in a controlled, precise and effective manner. This multifunctional nanorobot possesses significant potential for applications in sewage treatment, biomedicine, and other fields."
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