3Z and biotx.ai Forge Partnership to Advance ADHD Drug Development Using AI Modelling

The partnership between 3Z and biotx.ai aims to establish a robust bridge from animal discovery studies to human clinical trials. By utilizing comprehensive AI-powered human genetics-based modelling, the involvement of the lead therapeutic targets in ADHD will be thoroughly explored. This study will provide insights into the targets' effects on the disorder, predict potential effects on other diseases or disorders, and assess metabolic changes. Real-world zebrafish measurements will be compared to validate the predictions, ultimately simulating a Phase II clinical trial.

The partnership between 3Z and biotx.ai aims to establish a robust bridge from animal discovery studies to human clinical trials. By utilizing comprehensive AI-powered human genetics-based modelling, the involvement of the lead therapeutic targets in ADHD will be thoroughly explored. This study will provide insights into the targets' effects on the disorder, predict potential effects on other diseases or disorders, and assess metabolic changes. Real-world zebrafish measurements will be compared to validate the predictions, ultimately simulating a Phase II clinical trial.

The outcome of this groundbreaking AI study will provide a prediction value for the trial's success or failure, effectively de-risking the lead compound as it enters a real-world clinical trial. By employing AI modelling, the partnership aims to accelerate the drug development process and improve the efficiency of translating findings from animal models to human trials.

Dr. Karl Karlsson, CEO of 3Z and an expert in behavioral neuroscience and biomedical engineering, emphasized the significance of this partnership, stating, "We are entering a new era in drug discovery and development, where AI has the potential to revolutionize the industry. The animal models we develop focus on disorders and diseases that manifest as dysregulation within neuronal networks, which is probably the most challenging aspect to simulate successfully. However, we can model the effects of the drugs we identify on specific genetic targets, enabling us to obtain critical information and significantly reduce the risk of failure going forward."

For more information about 3Z and biotx.ai, please visit their respective websites at: http://www.3z.is) and http://www.biotx.ai, or follow them on LinkedIn.

About 3Z:

3Z is a Reykjavik-based drug discovery company specializing in genetically engineered models of human central nervous system disorders. Their innovative zebrafish screening platform enables the identification and validation of potential therapeutics for a range of neurological conditions.

About biotx.ai:

biotx.ai developed a causal AI mimicking clinical trials in human genetic data. Internally this has led to 2 drugs, each with high probability of success, now in clinical development. Now biotx.ai makes the same technology  available to biotech and Pharmas.

For media inquiries please contact: 

Dr. Karl Æ. Karlsson  
Email: Karlsson@3z.is  
Tel: +354-8256467

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