Cell Study by SDU and PKU Researchers Reveals Novel Mechanism to Regulate Glucose Metabolism

This research is the first to reveal that the microbial-derived bile acid Trp-CA improves glucose homeostasis by activating MRGPRE. It provides a new potential drug target and therapeutic strategy for Type 2 Diabetes (T2D) treatment. Furthermore, the identification of the microbial origin of Trp-CA offers a new microbial therapeutic strategy for diabetes intervention. This research is the first to reveal that the microbial-derived bile acid Trp-CA improves glucose homeostasis by activating MRGPRE...

JINAN, China, 23/06/2025 (informazione.news - comunicati stampa - salute e benessere)

This research is the first to reveal that the microbial-derived bile acid Trp-CA improves glucose homeostasis by activating MRGPRE. It provides a new potential drug target and therapeutic strategy for Type 2 Diabetes (T2D) treatment. Furthermore, the identification of the microbial origin of Trp-CA offers a new microbial therapeutic strategy for diabetes intervention.

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