HaemaLogiX wins "Most Promising CAR-T Pipeline in APAC" at the Asia Pacific CGT¹ Excellence Awards 2025
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"This award is wonderful recognition of not just our science, but also the dedication and vision that drives our work," said Rosanne Dunn, Founder and Chief Scientific Officer of HaemaLogiX. "We're honoured to be recognised in such exceptional company - a field of the region's top innovators - all striving to redefine what's possible in CAR T-cell therapy. We're more determined than ever to advance transformative therapies, particularly for multiple myeloma – the world's second largest blood cancer and a disease for which there is currently no cure."
HaemaLogiX's immunotherapies bind to unexploited and unique targets (antigens) on the surface of cancerous plasma cells. These antigens are called kappa myeloma antigen (KMA) and lambda myeloma antigen (LMA), and importantly they are not present on normal plasma cells. This provides on-target efficacy and reduced off-tumour toxicity thus preserving immune function and offering a key differentiation to current treatment options. Approximately 70% of multiple myeloma patients are kappa-type and would express KMA and 30% are lambda-type and would express LMA on their myeloma plasma cells. Multiple myeloma patients only express one or the other antigen on their myeloma plasma cells.
About Multiple Myeloma
Multiple myeloma is a malignant disorder of plasma cells within the bone marrow. The world's second most common blood cancer, approximately 188,000 new cases are diagnosed globally each year. Approximately 60% of patients fail standard-of-care and progress to subsequent lines of therapy with poorer outcomes, with ~42% of patients not living more than five years past diagnosis. This underscores the great unmet medical need for safer and more efficacious treatment options.
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References:
1. CGT = Cell and Gene Therapy
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