Scienza e Tecnologia
Pharming announces the filing of its 2021 Annual Report, with Form 20-F also filed with the U.S. Securities and Exchange Commission and convenes its 2022 AGM
The Annual Report is available on the Company's website under Investors/Financial Documents, https://www.pharming.com/investors/financial-documents. The Form 20-F is also available the Company's website under Investors/SEC filings https://www.pharming.com/investors/sec-filings.
In addition, the Company's 2022 Annual General Meeting (AGM) will be held on Wednesday 18 May 2022 at 2:00 pm (CEST) . The Notice to Convene, Explanatory Notes, meeting documents and Form of Proxy can be found on the Company's website, www.pharming.com under Investors/Shareholders' Meetings.
Pharming Group N.V. is a global, commercial stage biopharmaceutical company developing innovative protein replacement therapies and precision medicines for the treatment of rare diseases and unmet medical needs.
The flagship of our portfolio is our recombinant human C1 esterase inhibitor (rhC1INH) franchise. C1INH is a naturally occurring protein that down regulates the complement and contact cascades in order to control inflammation in affected tissues.
Our lead product, RUCONEST®, is the first and only plasma-free rhC1INH protein replacement therapy. It is approved for the treatment of acute hereditary angioedema (HAE) attacks. We are commercializing RUCONEST® in the United States , the European Union and the United Kingdom through our own sales and marketing organization, and the rest of the world through our distribution network.
In addition, we are investigating the clinical efficacy of rhC1INH in the treatment of further indications, including pre-eclampsia, acute kidney injury and severe pneumonia as a result of COVID-19 infections.
We are also studying our oral precision medicine, leniolisib (a phosphoinositide 3-kinase delta, or PI3K delta, inhibitor), for the treatment of activated PI3K delta syndrome, or APDS. World-wide rights for leniolisib were licensed from Novartis AG in 2019. Leniolisib met both of its primary end points in a registration enabling Phase 2/3 study in the United States and Europe . We are targeting global regulatory filings for leniolisib from Q2 2022 onwards.
Additionally, we entered into a strategic collaboration with Orchard Therapeutics to research, develop, manufacture and commercialize OTL-105, a newly disclosed investigational ex-vivo autologous hematopoietic stem cell (HSC) gene therapy for the treatment of HAE.
Furthermore, we are leveraging our transgenic manufacturing technology to develop next-generation protein replacement therapies, most notably for Pompe disease, which is currently in preclinical development.
Sijmen de Vries, CEO: T: +31 71 524 7400
Susanne Embleton , Investor Relations Manager: T: +31 71 524 7400 E: investor@pharming.com
Victoria Foster Mitchell / Alex Shaw
T: +44 203 727 1000
Jim Polson
Leon Melens
T: +31 6 53 81 64 27
E: pharming@lifespring.nl
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