Salute e Benessere
EQT Life Sciences portfolio company VarmX partners with CSL in a strategic collaboration and option agreement worth up to USD 2.2 billion
VMX-C001 is an investigational product, designed to bypass the FXa anticoagulation activity and swiftly restore coagulation in patients in urgent surgery and severe bleeding situations. Under the terms of the strategic collaboration agreement, CSL will fully fund VarmX's global Phase 3 trial evaluating VMX-C001. CSL will also fully fund and support VarmX in late-stage product development, manufacturing and pre-launch commercial and medical affairs activities.
EQT Life Sciences originally invested in VarmX in 2020, co-leading the company's Series B financing, investing from its LSP 6 fund. At the time, VMX-C001 was still in preclinical stages but with EQT's support, the company successfully completed a first-in-human clinical study and recently obtained FDA clearance for its Investigational New Drug (IND) application to start a global registrational Phase 3 trial with VMX-C001.
, added: "We are very proud to see that VarmX is, together with CSL, advancing its truly game-changing approach for this large unmet need in the emergency care setting. FDA's recent granting of Fast Track Designation for VMX-C001 aims to shorten the time to market, further recognizing the company's unique opportunity as well as the promise for patients."
, said: "The collaboration with CSL represents a transformative step for VarmX. By securing full funding for the registrational trial, product development, CMC and pre-launch activities, we are well positioned to bring VMX-C001 to patients. We are proud to partner with CSL, whose expertise and global reach will be invaluable as we move forward."
, commented: "We are excited to partner with VarmX to develop a novel treatment and address a significant unmet need aligning strongly with our strategic ambition to deliver enduring patient impact. It also aligns with our portfolio of medicines designed to minimize bleeding, preserve a patient's own blood supply, improve surgical and medical outcomes and support global public health approaches to patient blood management."
CSL will make an upfront payment to VarmX shareholders of USD 117 million upon closing of the transaction for an exclusive option to acquire the company. CSL will have the right to exercise the option upon Phase 3 data. Subject to the achievement of certain milestones, following the exercise of the option and customary regulatory clearances, VarmX shareholders will receive a further USD 388 million in acquisition and additional payments up to the commercial launch of VMX-C001 and up to USD 1.7 billion in sales-based success milestones thereafter.
EQT Press Office, press@eqtpartners.com
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