Okayama University research: Nanotechnology for making cancer drugs more accessible to the brain

https://www.okayama-u.ac.jp/up_load_files/research_highlights/129_image_1.jpg https://www.okayama-u.ac.jp/up_load_files/research_highlights/129_image_1.jpg Caption: Colonies of cells treated with the A6K-BSH complex reduced greatly when exposed to radiation for 15 minutes or more suggesting that the growth of cancer cells was halted. Reference Hiroyuki Michiue, Mizuki Kitamatsu,Asami Fukunaga,Nobushige Tsuboi,Atsushi Fujimura,Hiroaki Matsushita,Kazuyo Igawa, Tomonari...

https://www.okayama-u.ac.jp/up_load_files/research_highlights/129_image_1.jpg

Caption: Colonies of cells treated with the A6K-BSH complex reduced greatly when exposed to radiation for 15 minutes or more suggesting that the growth of cancer cells was halted.

Reference
Hiroyuki Michiue, Mizuki Kitamatsu, Asami Fukunaga, Nobushige Tsuboi, Atsushi Fujimura, Hiroaki Matsushita, Kazuyo Igawa, Tomonari Kasai, Natsuko Kondo, Hideki Matsui, Shuichi Furuya. Self-assembling A6K peptide nanotubes as a mercaptoundecahydrododecaborate (BSH) delivery system for boron neutron capture therapy (BNCT). Journal of Controlled Release, 2020 Nov 11;330:788-796.
DOI : 10.1016/j.jconrel.2020.11.001
https://www.sciencedirect.com/science/article/pii/S0168365920306489?via=ihub

Reference (Okayama Univ. e-Bulletin): Professor MICHIUE's team
OU-MRU Vol.14：Simplified boron compound may treat brain tumours

Correspondence to
Associate professor MICHIUE Hiroyuki, M.D., Ph.D.
Neutron Therapy Research Center, Okayama University,
Shikata-cho 2-5-1, Okayama-city, Okayama 700-8558,
Japan
E-mail: hmichiue(a)md.okayama-u.ac.jp
https://www.ntrc.okayama-u.ac.jp/en/index.html


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