Oligonucleotide Synthesis Market to Exceed 9.9 billion by 2035 Say, Roots Analysis
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LONDON, Jan. 10, 2024 /PRNewswire/ -- The global oligonucleotide synthesis market is anticipated to be worth USD 3.5 billion in 2023, and it is expected to reach 9.9 billion by 2035. It is estimated to grow at a compounded annual growth rate (CAGR) of 16.1% during the forecast period (2023-2035).
Oligonucleotides have seen a significant increase in applications, playing crucial roles in genetic and molecular testing, as well as therapeutic studies. Over 14 oligonucleotide-based therapies have been approved, with examples like AMONDYS 45 (2021) and Oxlumo™ (2020). Manufacturing oligonucleotides involves complex chemical synthesis, leading many in the field to rely on contract service providers due to challenges in purification and analytical expertise. The demand for effective targeted therapies, particularly post-COVID-19, has fueled an increase in oligonucleotide demand for testing kits. As a result, contract service providers are expanding to meet this growing demand. Positive clinical trial results and extensive research on oligonucleotides are expected to create lucrative opportunities for custom and contract service providers in the foreseeable future.
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Oligonucleotide Synthesis Market Report Scope:
Market Drivers
The drivers of the oligonucleotide synthesis market include the therapeutic potential of oligonucleotides, their crucial role in diagnostics and testing procedures, a growing pipeline of approved therapies, outsourcing trends due to synthesis complexity, increased demand for targeted therapies globally, the impact of the COVID-19 pandemic on testing kit development, positive clinical trial results, and ongoing technological advancements in synthesis methods. These factors collectively contribute to the market's growth, reflecting the expanding applications and demand for oligonucleotides in various fields.
Market Restraints
The oligonucleotide synthesis market faces several challenges, including the complexity of synthesis procedures, purification difficulties, gaps in analytical expertise, cost intensiveness, and regulatory constraints. Additionally, limited in-house manufacturing capabilities and the potential for supply chain disruptions pose restraints. Intense market competition contributes to pricing pressures and reduced profit margins. Overcoming these challenges requires ongoing innovation, investment in technology and workforce development, and strategic collaborations to navigate regulatory hurdles and ensure a robust and sustainable market for oligonucleotide synthesis.
Growth Factors
The growth factors for the oligonucleotide synthesis market include the expanding applications of oligonucleotides in genetic testing, diagnostics, and therapeutics. Oligonucleotides' therapeutic potential, demonstrated by successful clinical studies and approvals of therapies like AMONDYS 45 and Oxlumo™, contributes to market growth. The increasing demand for targeted therapies, outsourcing trends in manufacturing operations, and the surge in demand for oligonucleotides in COVID-19 testing kits further fuel market expansion. Additionally, technological advancements, positive clinical trial results, ongoing research activities, and strategic market expansion efforts by service providers collectively contribute to a positive outlook for the oligonucleotide synthesis market.
Recent Developments in Oligonucleotide Synthesis Market:
Several recent developments have taken place in the field of oligonucleotide synthesis. We have outlined some of these recent initiatives below. These developments, even if they took place post the release of our market report, substantiate the overall market trends that have been outlined in our analysis.
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Oligonucleotide Synthesis Market Segment (for Outsourcing)
Based on the type of oligonucleotide, the oligonucleotide synthesis market is segmented into Antisense, siRNA, shRNA, miRNA, and Others.
Based on the scale of operation, the oligonucleotide synthesis market is segmented into clinical and commercial operations.
Based on the type of operation, the oligonucleotide synthesis market is segmented into API and FDF.
Based on the size of the manufacturer, the oligonucleotide synthesis market is segmented into small, mid-sized, and large manufacturers.
Based on the key therapeutic area outsourced, the oligonucleotide synthesis market is segmented into autoimmune disorders, cardiovascular disorders, genetic disorders, infectious disorders, metabolic disorders, neurological disorders, oncological disorders, ophthalmic disorders, and other disorders.
Based on geographical region, the oligonucleotide synthesis market is segmented into North America, Europe, Asia-Pacific, and Rest of the World.
Key Companies Profiled
The market report also includes detailed profiles of key players (listed below) that offer oligonucleotide synthesis services and solutions:
It is worth highlighting here that in January 2023, Aurisco entered into a strategic collaboration with Cytiva to build its first OligoFlexfactory platform to strengthen its commercial production of nucleotides. Driven by ongoing collaborations, the oligonucleotide synthesis market is estimated to grow during the forecast period.
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About Roots Analysis
Roots Analysis is a global leader in the pharma/biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists, and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights. All reports provided by us are structured in a way that enables the reader to develop a thorough perspective on the given subject. Apart from writing reports on identified areas, we provide bespoke research/consulting services dedicated to serving our clients in the best possible way.
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