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Lonza's Synaffix Collaborates with Qurient Therapeutics to Enable Development of Dual-Payload ADC
The collaboration aims to develop a dual-payload ADC consisting of Synaffix's exatecan-based technology and Qurient's CDK7 inhibitor, aiming to target unmet medical needs in solid tumors. Under the terms of the agreement, Qurient will gain access to Lonza's clinical-stage, site-specific ADC technology platform powered by Synaffix services including GlycoConnect® antibody conjugation, HydraSpace® polar spacer, and exatecan-based linker-payload technologies, as well as Lonza's market-leading expertise and experience in developing and manufacturing bioconjugates.
Lonza will manufacture components related to its proprietary Synaffix technologies, and Qurient will perform the research, development, manufacturing and commercialization of the ADC, and manufacturing of Qurient's CDK7 inhibitor.
Synaffix B.V. is a biotechnology company that enables ADC product candidates using its clinical-stage, site-specific ADC technology platform based on GlycoConnect®, HydraSpace® and toxSYN® technologies, that together enable any company with an antibody to develop proprietary best-in-class ADC products under a single license from Synaffix.
The Synaffix platform enables a rapid timeline to clinic due to the established supply chain of technology components. Synaffix holds granted patents to its technology. The business model of Synaffix is target-specific technology out-licensing, as exemplified through its partner pipeline.
Synaffix was fully acquired by Lonza in June 2023 .
For more information about Synaffix's ADC platform technology, please visit: https://synaffix.com/platform/technology/
Lonza is one of the world's largest development and manufacturing organizations (CDMOs). Working across five continents, our global team of more than 19,000 colleagues works alongside pharma and biotech companies to turn their breakthrough innovations into viable therapies. We support our customers in bringing life-saving and life-enhancing treatments to patients worldwide with a combination of cutting-edge science, smart technology and lean manufacturing.
Our company generated sales of CHF 3.6 billion with a CORE EBITDA of CHF 1.1 billion in Half-Year 2025. Find out more at
Qurient Co., Ltd. is a public clinical-stage biotechnology company headquartered in South Korea and listed on KOSDAQ, with a mission to develop innovative medicines and targeted therapies across oncology and infectious diseases. The company's pipeline includes mocaciclib (Q901), a CDK7 inhibitor targeting transcriptionally addicted cancers; adrixetinib (Q702), an AXL/MER/CSF1R inhibitor being explored for chronic graft-versus-host disease (cGvHD) and oncology indications; and telacebec (Q203), a first-in-class antibiotic in late-stage development for Tuberculosis, Buruli ulcer and other mycobacterial diseases. Qurient combines strong translational research expertise with global partnerships to advance programs from discovery through clinical development. By strategically focusing on high-unmet-need indications such as hard-to-treat cancers, drug-resistant mycobacteria, and immune-driven diseases, Qurient positions itself at the intersection of precision oncology and infectious disease innovation. For more information, please visit www.qurient.com.
View original content:https://www.prnewswire.co.uk/news-releases/lonzas-synaffix-collaborates-with-qurient-therapeutics-to-enable-development-of-dual-payload-adc-302566445.html