MindRank Announces First-in-Human Phase 1 Study of MDR-001 in China

This FIH Phase 1 study is a randomized, double-blind, placebo-controlled, dose-escalation trial to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic effects of MDR-001 in healthy volunteers and patients with obesity or T2DM. This FIH Phase 1 study is a randomized, double-blind, placebo-controlled, dose-escalation trial to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic effects of MDR-001 in healthy volunteers and patients with obesity or T2DM...

This FIH Phase 1 study is a randomized, double-blind, placebo-controlled, dose-escalation trial to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic effects of MDR-001 in healthy volunteers and patients with obesity or T2DM.

About MDR-001

MDR-001 is a novel, β-arrestin 2 selective, orally bioavailable small-molecule GLP-1 RA discovered using MindRank's proprietary AI platform, Molecule Pro. MDR-001 has been tested comprehensively in preclinical studies and demonstrated excellent functional potency and selectivity, with favorable ADME properties and oral bioavailability, as well as desirable pharmacokinetics, safety and tolerability, indicating its best-in-class potential for the treatment of obesity and T2DM with large unmet medical needs.

About MindRank

MindRank is an artificial intelligence (AI)-empowered drug discovery company. By leveraging its proprietary AI platforms (PharmKG, Molecule Dance and Molecule Pro), the company aims to significantly accelerate the drug discovery process and deliver small molecule medicines with differentiations and clinical benefits.

For more information, visit www.mindrank.ai.
For BD inquiries, contact bd@mindrank.ai.

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