PeptiGrowth Inc. is Launching a Novel Synthetic Peptide: KGF alternative peptide (FGFR2b agonist)

About KGF alternative peptide (FGFR2b agonist) [Product code: PG-012] About KGF alternative peptide (FGFR2b agonist) [Product code: PG-012] PG-012, KGF alternative peptide, is a dimeric peptide composed of cyclic peptides designed to bind specifically to FGFR2b. Like KGF, PG-012 effectively interacts with FGFR2b and exhibits agonistic activity against FGFR2b (see diagram below). We conducted a comparative study on the functions of KGF alternative peptide (PG-012) and commercially...

About KGF alternative peptide (FGFR2b agonist) [Product code: PG-012]

PG-012, KGF alternative peptide, is a dimeric peptide composed of cyclic peptides designed to bind specifically to FGFR2b. Like KGF, PG-012 effectively interacts with FGFR2b and exhibits agonistic activity against FGFR2b (see diagram below).

We conducted a comparative study on the functions of KGF alternative peptide (PG-012) and commercially available recombinant KGF using FGFR2b-overexpressing BaF3 cells. We confirmed that the KGF alternative peptide activates ERK (upper left figure) and exhibits proliferation activity (upper right figure) in a manner similar to recombinant KGF at lower concentrations (ng/mL basis).

We anticipate that the KGF alternative peptide (PG-012) will be applicable in regenerative medicine and cell therapy, particularly in applications such as differentiation and proliferation of epidermal cells and cells derived from the endoderm, such as alveolar epithelial cells, islet cells, and hepatocytes, from pluripotent stem cells.

Product name: KGF alternative peptide (FGFR2b agonist)
Product code: PG-012
Product form: Lyophilized
Storage conditions: -20°C or less
Purity: ≥95% by HPLC
Molecular weight: 6018.40 (Acetate)
Size: 10 μg, 100 μg, 1 mg (volume per vial)
*This product can be provided with an Animal Component Free (ACF) certificate.
*This product is for testing and research use only (RUO).
*There is a possibility that the specifications can change.

If you would like to purchase our products, please contact us using the information below.

For customers who would like to purchase GMP compliant products as well as the above PG products in bulk scale, please contact us using the information below.

Contact Information

PeptiGrowth Inc.
Tel: + 81-(0)70-7789-3905
E-mail: [email protected] 

Development of other peptides from PeptiGrowth
We have developed alternative peptides targeting numerous growth factors and cytokines. To date, we have launched 12 products and plan to launch additional growth-factor alternative peptides targeting PDGF-AA and IL-15 by the end of 2025. 

Photo - https://mma.prnewswire.com/media/2653649/Mechanism_Action_PG_012_a_KGF_Alternative_Peptide.jpg
Photo - https://mma.prnewswire.com/media/2653650/ERK_phosphorylation_cell_proliferation_activity_PG_012_KGF_FGFR2b_overexpressing_BaF_cells.jpg
Logo - https://mma.prnewswire.com/media/2192331/PeptiGrowth_Inc_Logo.jpg

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