Publication relating to transparency notifications

REGULATED INFORMATIONPublication relating to transparency notificationsMont-Saint-Guibert(Belgium), October 3, 2025 , 10:30 pm CET / 4:30 pm ET –In accordance with article 14 of the Act of 2 May 2007 on the disclosure of large shareholdings, Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) announces that it received a transparency notification as detailed below.Vestal Point CapitalOn October 1, 2025, Nyxoah received a transparency notification from Vestal Point Capital...

REGULATED INFORMATION

Publication relating to transparency notifications

Mont-Saint-Guibert(Belgium), October 3, 2025, 10:30 pm CET / 4:30 pm ET – In accordance with article 14 of the Act of 2 May 2007 on the disclosure of large shareholdings, Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) announces that it received a transparency notification as detailed below.

Vestal Point Capital

On October 1, 2025, Nyxoah received a transparency notification from Vestal Point Capital following an acquisition or disposal of voting securities or voting rights. Based on the notification, Vestal Point Capital holds 1,113,575 voting rights, representing 2.97% of the total number of voting rights on September 24, 2025 (37,544,782).

The notification dated September 30, 2025 contains the following information:

• Reason for thenotification:
  • Acquisition or disposal of voting securities or voting rights
  • Downward crossing of the lowest threshold
• Notification by: a parent undertaking or a controlling person
• Persons subject to the notification requirement:
  • Vestal Point Capital, LLC (with address at 632 Broadway, Suite 602, New York, NY 10012, USA)
  • Vestal Point Capital, LP (with address at 632 Broadway, Suite 602, New York, NY 10012, USA)
  • Ryan Wilder (with address at 632 Broadway, Suite 602, New York, NY 10012, USA)
• Date on which the threshold was crossed: September 24, 2025
• Threshold that is crossed: 3%
• Denominator: 37,544,782
• Notifieddetails:

A) Voting rights	Previous notification	After the transaction
	# of voting rights	# of voting rights		% of voting rights
Holders of voting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
Ryan Wilder	0	0	0	0.00%	0.00%
Vestal Point Capital, LLC	0	0	0	0.00%	0.00%
Vestal Point Capital, LP	1,809,843	1,113,575	0	2.97%	0.00%
Subtotal	1,809,843	1,113,575		2.97%
	TOTAL	1,113,575		2.97%

• Full chain of controlled undertakings through which the holding is effectively held: Vestal Point Capital, LP (investment manager) is controlled by Vestal Point Capital, LLC (general partner). Vestal Point Capital, LLC is controlled by Mr. Ryan Wilder (managing member).
• Additional information: Vestal Point Capital, LP is the investment management company that can exercise the voting rights at its discretion, in the absence of specific instruction.

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Contact:
Nyxoah
John Landry, CFO
[email protected]

Attachment

• 2025 10 03 PR Transparency notification (Vestal Point) (ENG)